HS1BP3-IT1

Across TCGA pan-cancer cohorts, HS1BP3-IT1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated HS1BP3-IT1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher HS1BP3-IT1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated HS1BP3-IT1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and LGG show a favorable association.

KIRC, ACC, and LUSC are the cancer types where HS1BP3-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.746	0.536	<.001	166	view →
ACC	DFS	Median	All	0.506	0.800	<.001	77	view →
LUSC	OS	Quartile	All	0.713	0.847	<.001	58	view →
CESC	DFS	Tertile	All	0.384	0.680	.002	56	view →
THCA	OS	Quartile	II,III,IV	0.761	1.000	.004	25	view →
LGG	OS	Tertile	All	0.945	0.840	<.001	24	view →
SKCM	OS	Median	II,III,IV	0.881	0.800	.007	21	view →
HNSC	OS	Median	IV	0.487	0.770	.005	18	view →
CHOL	OS	Quartile	II,III,IV	0.273	0.865	.019	18	view →
BLCA	DFS	Tertile	All	0.414	0.243	.010	17	view →
COAD	DFS	Tertile	IV	0.704	0.376	.007	16	view →
MESO	DFS	Quartile	IV	0.100	0.610	.006	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

HS1BP3-IT1–KIRC (OS)

Open the KIRC breakdown →