HROB

Across TCGA patient cohorts, HROB RNA expression is significantly associated with the protein abundance of many other proteins, with 26,854 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HROB-associated proteins across cancer lineages are PRIM2, HAT1, and NCL_S67. Each is linked with HROB in more than 9 cancer types. Because this analysis shows association rather than direction, both HROB-to-partner and partner-to-HROB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HROB versus PRIM2 in LSCC, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HROB→partner) and Y-score (partner→HROB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PRIM2 →	+0.462	+0.938	<.001	<.001	3	10
LUAD	HAT1 →	+0.435	+0.891	<.001	<.001	3	10
LUAD	NCL_S67 →	+1.032	+1.119	<.001	<.001	3	10
LUAD	RRM2 →	+0.904	+1.193	<.001	<.001	3	10
HNSC	LIG1 →	+0.445	+0.836	<.001	<.001	3	10
LUAD	MCM2 →	+0.885	+1.293	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 26,854 associations by consensus.

HROB vs PRIM2 — LSCC

Explore this scatter interactively →