HROB

Across TCGA cell cohorts, HROB RNA expression is significantly associated with the go_rna of many other GO terms, with 4,224 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HROB-associated GO terms across cancer lineages are Double-strand break repair via homologous recombination, Recombinational repair, and Mitotic DNA replication. Each is linked with HROB in more than 19 cancer types. Because this analysis shows association rather than direction, both HROB-to-partner and partner-to-HROB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Double-strand break repair via homologous recombination grouped by HROB-low versus HROB-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HROB→partner) and Y-score (partner→HROB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Double-strand break repair via homologous recombination →	+0.111	+0.875	.001	.003	3	20
OESOPHAGUS	Recombinational repair →	+0.115	+0.831	.001	.003	3	20
PANCREAS	Mitotic DNA replication →	+0.248	+1.307	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	DNA strand elongation →	+0.189	+0.918	<.001	<.001	3	19
BONE	Nuclear DNA replication →	+0.186	+1.161	.004	<.001	3	19
PANCREAS	DNA replication →	+0.141	+1.318	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,224 associations by consensus.

Double-strand break repair via homologous recombination by HROB expression — OESOPHAGUS

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