Across TCGA patient cohorts, HRNR protein abundance is significantly associated with the RNA expression of many other genes, with 1,626 significant associations in total. OV shows the largest number of these associations.

The most reproducible HRNR-associated genes across cancer lineages are CCZ1B, MIS18A, and TSEN34. Each is linked with HRNR in more than 1 cancer types. Because this analysis shows association rather than direction, both HRNR-to-partner and partner-to-HRNR results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HRNR→partner) and Y-score (partner→HRNR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CCZ1B →	-0.804	-2.354	<.001	<.001	3	2
OV	MIS18A →	-0.822	-1.824	.002	.007	3	2
OV	TSEN34 →	-0.688	-1.583	.001	.005	3	2
OV	LAGE3 →	-1.196	-2.369	.004	.002	3	2
OV	SETP8 →	-1.312	-1.461	<.001	.007	3	2
OV	HMGB1P10 →	-2.132	-1.422	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,626 associations by consensus.

Exploration

HRNR survival (RNA) · tumor vs normal (RNA) · all HRNR data types