HRK

Across TCGA cell cohorts, HRK RNA expression is significantly associated with the RNA expression of many other genes, with 10,069 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HRK-associated genes across cancer lineages are CASKIN1, ADAM11, and ALDH5A1. Each is linked with HRK in more than 5 cancer types. Because this analysis shows association rather than direction, both HRK-to-partner and partner-to-HRK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HRK versus CASKIN1 in LARGE_INTESTINE, with a Pearson correlation of 0.34.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HRK→partner) and Y-score (partner→HRK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CASKIN1 →	+0.850	+0.440	<.001	.003	3	6
SOFT_TISSUE	ADAM11 →	+1.302	+0.763	<.001	<.001	3	6
BLOOD_Lymphoma	ALDH5A1 →	+3.868	+2.008	<.001	<.001	3	6
BLOOD_Lymphoma	RNF144B →	+2.973	+1.678	<.001	<.001	3	6
BONE	NSG1 →	+3.459	+1.749	<.001	<.001	3	5
LUNG_NSCLC_LUAD	ARID2 →	+0.813	+0.755	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,069 associations by consensus.

HRK vs CASKIN1 — LARGE_INTESTINE

Explore this scatter interactively →