HRH4

Across TCGA patient cohorts, HRH4 protein abundance is significantly associated with the RNA expression of many other genes, with 2,452 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HRH4-associated genes across cancer lineages are RAB36, NEFH, and HMOX1. Each is linked with HRH4 in more than 1 cancer types. Because this analysis shows association rather than direction, both HRH4-to-partner and partner-to-HRH4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HRH4 versus RAB36 in GBM, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HRH4→partner) and Y-score (partner→HRH4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RAB36 →	-0.857	-0.668	<.001	.003	3	1
GBM	NEFH →	+1.243	+0.810	.002	.001	3	1
GBM	HMOX1 →	-1.338	-0.591	<.001	.002	3	1
GBM	SYNGR1 →	+1.048	+0.561	<.001	.006	3	1
GBM	PNPLA5 →	+0.304	+0.845	<.001	<.001	3	1
GBM	MYH9 →	-0.624	-0.663	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,452 associations by consensus.

HRH4 vs RAB36 — GBM

Explore this scatter interactively →