HRC

Across TCGA patient cohorts, HRC RNA expression is significantly associated with the protein abundance of many other proteins, with 19,971 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible HRC-associated proteins across cancer lineages are VWF, TNXB, and PLAC9. Each is linked with HRC in more than 8 cancer types. Because this analysis shows association rather than direction, both HRC-to-partner and partner-to-HRC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HRC versus VWF in BRCA, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HRC→partner) and Y-score (partner→HRC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	VWF →	+0.724	+0.803	<.001	<.001	3	9
CCRCC	TNXB →	+0.853	+0.853	<.001	<.001	3	8
CCRCC	PLAC9 →	+0.850	+0.852	<.001	<.001	3	8
BRCA	CAVIN2 →	+0.923	+0.564	<.001	<.001	3	8
CCRCC	MMRN2 →	+0.649	+1.017	<.001	<.001	3	8
BRCA	CNRIP1 →	+0.646	+0.410	<.001	.006	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,971 associations by consensus.

HRC vs VWF — BRCA

Explore this scatter interactively →