HR

Across TCGA cell cohorts, HR RNA expression is significantly associated with the RNA expression of many other genes, with 10,274 significant associations in total. BONE shows the largest number of these associations.

The most reproducible HR-associated genes across cancer lineages are GAL3ST4, CELSR2, and EFNB1. Each is linked with HR in more than 7 cancer types. Because this analysis shows association rather than direction, both HR-to-partner and partner-to-HR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HR versus GAL3ST4 in OESOPHAGUS, with a Pearson correlation of 0.59.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HR→partner) and Y-score (partner→HR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	GAL3ST4 →	+1.990	+2.450	<.001	.004	3	8
BONE	CELSR2 →	+2.247	+2.478	<.001	<.001	3	8
BONE	EFNB1 →	+2.987	+2.338	<.001	<.001	3	8
URINARY_TRACT	DDR1 →	+2.165	+2.635	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	REEP4 →	+1.082	+2.154	<.001	<.001	3	7
BREAST	CYP2D6 →	+0.731	+1.536	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,274 associations by consensus.

HR vs GAL3ST4 — OESOPHAGUS

Explore this scatter interactively →