HPYR1

Across TCGA patient cohorts, HPYR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,926 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HPYR1-associated GO terms across cancer lineages are Positive regulation of transcription elongation by RNA polymerase II, Microtubule polymerization, and Positive regulation of double-strand break repair. Each is linked with HPYR1 in more than 17 cancer types. Because this analysis shows association rather than direction, both HPYR1-to-partner and partner-to-HPYR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of transcription elongation by RNA polymerase II grouped by HPYR1-low versus HPYR1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HPYR1→partner) and Y-score (partner→HPYR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of transcription elongation by RNA polymerase II →	+0.076	+0.060	<.001	<.001	3	18
STAD	Microtubule polymerization →	+0.070	+0.059	<.001	<.001	3	18
STAD	Positive regulation of double-strand break repair →	+0.074	+0.053	<.001	<.001	3	17
STAD	Vesicle localization →	+0.070	+0.055	<.001	<.001	3	17
STAD	Regulation of microtubule cytoskeleton organization →	+0.068	+0.060	<.001	<.001	3	17
STAD	Regulation of calcium ion export across plasma membrane →	+0.059	+0.066	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,926 associations by consensus.

Positive regulation of transcription elongation by RNA polymerase II by HPYR1 expression — STAD

Explore this box plot interactively →