HPRT1P2

Across TCGA patient cohorts, HPRT1P2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,066 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HPRT1P2-associated GO terms across cancer lineages are Ribose phosphate biosynthetic process, Obsolete positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus, and Meiotic sister chromatid cohesion. Each is linked with HPRT1P2 in more than 4 cancer types. Because this analysis shows association rather than direction, both HPRT1P2-to-partner and partner-to-HPRT1P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribose phosphate biosynthetic process grouped by HPRT1P2-low versus HPRT1P2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HPRT1P2→partner) and Y-score (partner→HPRT1P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Ribose phosphate biosynthetic process →	+0.115	+0.121	<.001	<.001	3	5
STAD	Obsolete positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus →	+0.094	+0.130	<.001	<.001	3	4
STAD	Meiotic sister chromatid cohesion →	+0.083	+0.108	<.001	<.001	3	4
STAD	Positive regulation of cold-induced thermogenesis →	+0.074	+0.122	<.001	<.001	3	4
STAD	Positive regulation of amyloid-beta formation →	+0.075	+0.094	<.001	<.001	3	4
STAD	Proton transmembrane transport →	+0.097	+0.112	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,066 associations by consensus.

Ribose phosphate biosynthetic process by HPRT1P2 expression — STAD

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