HPRT1P2

Across TCGA pan-cancer cohorts, HPRT1P2 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated HPRT1P2 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher HPRT1P2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated HPRT1P2 expression acts as an unfavorable survival marker, although some lineages such as STAD and PAAD show a favorable association.

READ, BLCA, and LIHC are the cancer types where HPRT1P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Tertile	III,IV	0.289	0.932	<.001	81	view →
BLCA	OS	Tertile	All	0.155	0.618	.001	72	view →
LIHC	DFS	Tertile	All	0.107	0.544	.006	45	view →
KIRP	OS	Tertile	II,III,IV	0.161	0.771	.002	39	view →
STAD	DFS	Tertile	IV	0.743	0.247	.014	36	view →
KICH	DFS	Tertile	All	0.162	0.862	.014	30	view →
PAAD	DFS	Tertile	All	1.000	0.257	.010	27	view →
ESCA	DFS	Tertile	All	0.148	0.673	.040	18	view →
KIRC	DFS	Tertile	IV	0.127	0.630	.039	18	view →
LUSC	DFS	Tertile	III,IV	0.010	0.754	<.001	18	view →
OV	DFS	Tertile	III,IV	0.879	0.526	.049	6	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

HPRT1P2–READ (OS)

Open the READ breakdown →