HPRT1

Across TCGA patient cohorts, HPRT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,894 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HPRT1-associated proteins across cancer lineages are HIRIP3_S125, TK1, and WDHD1. Each is linked with HPRT1 in more than 5 cancer types. Because this analysis shows association rather than direction, both HPRT1-to-partner and partner-to-HPRT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HPRT1 versus HIRIP3_S125 in OV, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HPRT1→partner) and Y-score (partner→HPRT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HIRIP3_S125 →	+0.719	+0.579	.002	.004	3	6
UCEC	TK1 →	+0.646	+0.577	<.001	.004	3	6
LUAD	WDHD1 →	+0.636	+0.638	<.001	<.001	3	6
UCEC	PCNA →	+0.526	+0.507	<.001	.006	3	6
OV	PHF6 →	+0.413	+0.638	.002	.008	3	6
BRCA	HIRIP3_S227 →	+0.605	+0.591	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,894 associations by consensus.

HPRT1 vs HIRIP3_S125 — OV

Explore this scatter interactively →