Across TCGA patient cohorts, HPN-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,348 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HPN-AS1-associated proteins across cancer lineages are LRP2, ANXA1, and BICD2. Each is linked with HPN-AS1 in more than 4 cancer types. Because this analysis shows association rather than direction, both HPN-AS1-to-partner and partner-to-HPN-AS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HPN-AS1→partner) and Y-score (partner→HPN-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LRP2 →	+0.984	+0.477	<.001	.008	3	5
UCEC	ANXA1 →	-0.518	-0.665	<.001	<.001	3	4
HNSC	BICD2 →	-0.430	-0.410	<.001	.005	3	4
GBM	CACNA2D2 →	+0.730	+0.328	<.001	.002	3	4
BRCA	DDAH1 →	+0.733	+0.764	<.001	<.001	3	4
HNSC	MYEF2 →	+0.608	+0.545	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,348 associations by consensus.

Exploration

HPN-AS1 survival (RNA) · tumor vs normal (RNA) · all HPN-AS1 data types