HOXD9

Across TCGA patient cohorts, HOXD9 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,998 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HOXD9-associated proteins across cancer lineages are PPM1F, SORBS3, and SSC5D. Each is linked with HOXD9 in more than 4 cancer types. Because this analysis shows association rather than direction, both HOXD9-to-partner and partner-to-HOXD9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXD9 versus PPM1F in UCEC, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXD9→partner) and Y-score (partner→HOXD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PPM1F →	+0.314	+0.546	<.001	<.001	3	5
UCEC	SORBS3 →	+0.551	+0.591	<.001	<.001	3	4
BRCA	SSC5D →	+0.828	+1.055	<.001	<.001	3	4
UCEC	THBS3 →	+0.669	+0.683	<.001	<.001	3	4
BRCA	TIMP2 →	+0.672	+0.624	<.001	.001	3	4
BRCA	TLN2 →	+0.539	+0.605	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,998 associations by consensus.

HOXD9 vs PPM1F — UCEC

Explore this scatter interactively →