HOXD10

Across TCGA patient cohorts, HOXD10 protein abundance is significantly associated with the RNA expression of many other genes, with 2,805 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HOXD10-associated genes across cancer lineages are TCF20, TIMP3, and ZBED4. Each is linked with HOXD10 in more than 1 cancer types. Because this analysis shows association rather than direction, both HOXD10-to-partner and partner-to-HOXD10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXD10 versus TCF20 in UCEC, with a Pearson correlation of -0.26.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXD10→partner) and Y-score (partner→HOXD10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TCF20 →	-0.381	-0.412	.009	.002	3	1
UCEC	TIMP3 →	+1.107	+0.540	.005	.001	3	1
UCEC	ZBED4 →	-0.408	-0.477	<.001	<.001	3	1
UCEC	CTSG →	+0.763	+0.449	.002	.008	3	1
UCEC	TRIM9 →	+0.679	+0.617	.001	<.001	3	1
UCEC	CCDC198 →	+0.879	+0.413	.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,805 associations by consensus.

HOXD10 vs TCF20 — UCEC

Explore this scatter interactively →