HOXD10

Across TCGA cell cohorts, HOXD10 mutation is significantly associated with the drug of many other genes, with 13 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HOXD10-associated genes across cancer lineages are 123829, AT7867, and Entospletinib. Each is linked with HOXD10 in more than 1 cancer types. Because this analysis shows association rather than direction, both HOXD10-to-partner and partner-to-HOXD10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 123829 grouped by HOXD10-low versus HOXD10-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXD10→partner) and Y-score (partner→HOXD10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	123829 →	+0.592	+2.649	.042	.046	3	1
LARGE_INTESTINE	AT7867 →	+0.534	+2.652	.026	.045	3	1
LARGE_INTESTINE	Entospletinib →	+0.378	+2.646	.049	.047	1	1
LARGE_INTESTINE	GSK2110183B →	+0.665	+2.649	.028	.046	1	1
LARGE_INTESTINE	Dactinomycin →	+0.642	+2.649	.005	.046	1	1
LARGE_INTESTINE	50869 →	+0.470	+2.649	.025	.046	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

123829 by HOXD10 expression — LARGE_INTESTINE

Explore this box plot interactively →