HOXD1

Across TCGA patient cohorts, HOXD1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,301 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HOXD1-associated proteins across cancer lineages are HOXD1_S193, INPP1, and MRPL1. Each is linked with HOXD1 in more than 5 cancer types. Because this analysis shows association rather than direction, both HOXD1-to-partner and partner-to-HOXD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXD1 versus HOXD1_S193 in LUAD, with a Pearson correlation of 0.75.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXD1→partner) and Y-score (partner→HOXD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	HOXD1_S193 →	+1.712	+1.730	<.001	<.001	3	6
COAD	INPP1 →	+0.395	+0.646	<.001	<.001	3	4
COAD	MRPL1 →	-0.301	-0.325	<.001	<.001	3	4
COAD	MRPS31 →	-0.413	-0.615	<.001	<.001	3	4
GBM	STXBP1 →	+0.589	+0.309	<.001	<.001	3	4
OV	ZNF800_S317 →	-0.924	-1.422	.006	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,301 associations by consensus.

HOXD1 vs HOXD1_S193 — LUAD

Explore this scatter interactively →