HOXC9

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HOXC9 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HOXC9-associated genes across cancer lineages are Preadipocytes and aDC. Each is linked with HOXC9 in more than 1 cancer types. Because this analysis shows association rather than direction, both HOXC9-to-partner and partner-to-HOXC9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Preadipocytes grouped by HOXC9-low versus HOXC9-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXC9→partner) and Y-score (partner→HOXC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADPreadipocytes →+0.061+4.754<.001.00331
UCECaDC →+0.115+3.010.007.02011
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Preadipocytes by HOXC9 expression — COAD

Box plot of Preadipocytes in HOXC9-low vs HOXC9-high samples in COAD.

Explore this box plot interactively →

Exploration