HOXC9

Across TCGA cell cohorts, HOXC9 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,934 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HOXC9-associated GO terms across cancer lineages are Cellular senescence, Lipoprotein transport, and Nucleic acid transport. Each is linked with HOXC9 in more than 7 cancer types. Because this analysis shows association rather than direction, both HOXC9-to-partner and partner-to-HOXC9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular senescence grouped by HOXC9-low versus HOXC9-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXC9→partner) and Y-score (partner→HOXC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Cellular senescence →	+0.094	+1.222	<.001	<.001	3	7
SOFT_TISSUE	Lipoprotein transport →	+0.129	+1.645	<.001	.001	3	7
LUNG_NSCLC_LUSC	Nucleic acid transport →	+0.095	+1.818	.001	.009	3	7
LUNG_NSCLC_LUSC	RNA transport →	+0.095	+1.818	.001	.009	3	7
BONE	Establishment of RNA localization →	+0.088	+0.765	<.001	.002	3	7
LUNG_NSCLC_LUAD	Negative regulation of hippo signaling →	+0.061	+1.131	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,934 associations by consensus.

Cellular senescence by HOXC9 expression — BONE

Explore this box plot interactively →