HOXC9

Across TCGA cell cohorts, HOXC9 mutation is significantly associated with the drug of many other genes, with 18 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HOXC9-associated genes across cancer lineages are KU-55933, TAF1_5496, and GSK2276186C. Each is linked with HOXC9 in more than 1 cancer types. Because this analysis shows association rather than direction, both HOXC9-to-partner and partner-to-HOXC9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KU-55933 grouped by HOXC9-low versus HOXC9-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXC9→partner) and Y-score (partner→HOXC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	KU-55933 →	+0.470	+2.807	.008	.046	3	1
LARGE_INTESTINE	TAF1_5496 →	+0.446	+3.000	.036	.017	3	1
LARGE_INTESTINE	GSK2276186C →	+0.499	+2.871	.022	.021	3	1
LARGE_INTESTINE	GW-2580 →	+0.304	+3.008	.012	.016	3	1
LARGE_INTESTINE	SU11274 →	+0.548	+2.874	.004	.021	3	1
LARGE_INTESTINE	KIN001-042 →	+0.337	+2.874	.001	.021	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

KU-55933 by HOXC9 expression — LARGE_INTESTINE

Explore this box plot interactively →