Across TCGA patient cohorts, HOXC6 protein abundance is significantly associated with the RNA expression of many other genes, with 140 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HOXC6-associated genes across cancer lineages are SOD3, DUSP6, and MBNL2. Each is linked with HOXC6 in more than 1 cancer types. Because this analysis shows association rather than direction, both HOXC6-to-partner and partner-to-HOXC6 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXC6→partner) and Y-score (partner→HOXC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SOD3 →	+3.223	+0.563	.004	.004	3	1
BRCA	DUSP6 →	+1.508	+0.613	.001	.009	3	1
BRCA	MBNL2 →	+1.190	+0.563	.003	.004	3	1
BRCA	ALDH4A1 →	+0.722	+0.613	.004	.009	3	1
BRCA	STK32C →	-1.206	-0.563	.003	.004	3	1
BRCA	LGI3 →	+0.101	+0.613	.005	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 140 associations by consensus.

Exploration

HOXC6 survival (RNA) · tumor vs normal (RNA) · all HOXC6 data types