HOXC6

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HOXC6 mutation is significantly associated with the RNA expression of many other genes, with 3,521 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HOXC6-associated genes across cancer lineages are RNU6-1276P, NMS, and RNA5SP412. Each is linked with HOXC6 in more than 1 cancer types. Because this analysis shows association rather than direction, both HOXC6-to-partner and partner-to-HOXC6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXC6→partner) and Y-score (partner→HOXC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCARNU6-1276P →+0.244+4.433<.001.00732
BLCANMS →+0.104+4.704<.001.00532
UCECRNA5SP412 →+0.638+2.230<.001<.00132
LUSCRNU6-996P →+0.450+7.924<.001.00832
LUSCRNU6-224P →+0.451+7.924<.001.00832
BLCASERPINB8P1 →+0.101+6.466<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,521 associations by consensus.

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