Across TCGA cell cohorts, HOXC6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,102 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HOXC6-associated GO terms across cancer lineages are Regulation of nucleotide-excision repair, Negative regulation of hippo signaling, and Transcription initiation at RNA polymerase II promoter. Each is linked with HOXC6 in more than 9 cancer types. Because this analysis shows association rather than direction, both HOXC6-to-partner and partner-to-HOXC6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXC6→partner) and Y-score (partner→HOXC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of nucleotide-excision repair →	+0.099	+1.351	.009	.003	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of hippo signaling →	+0.098	+1.029	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Transcription initiation at RNA polymerase II promoter →	+0.073	+0.885	.001	.005	2	10
BONE	Heterochromatin formation →	+0.077	+1.493	<.001	<.001	3	9
LARGE_INTESTINE	DNA-templated transcription initiation →	+0.063	+1.521	<.001	<.001	3	9
SKIN	Cellular response to acidic pH →	-0.126	-0.691	.005	.005	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,102 associations by consensus.

Exploration

HOXC6 survival (RNA) · tumor vs normal (RNA) · all HOXC6 data types