Across TCGA cell cohorts, HOXC6 protein abundance is significantly associated with the RNA expression of many other genes, with 2,461 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HOXC6-associated genes across cancer lineages are SMAD7, FUCA2, and HERC3. Each is linked with HOXC6 in more than 6 cancer types. Because this analysis shows association rather than direction, both HOXC6-to-partner and partner-to-HOXC6 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXC6→partner) and Y-score (partner→HOXC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	SMAD7 →	-1.203	-0.578	.003	.002	3	7
STOMACH	FUCA2 →	-1.769	-0.803	<.001	<.001	3	7
LUNG_NSCLC_LUAD	HERC3 →	-0.917	-0.525	.002	<.001	2	7
LUNG_SCLC	THOC3 →	+1.000	+0.819	<.001	<.001	3	6
BONE	LAMP1 →	-1.445	-0.557	.006	.003	2	7
CNS	ABHD4 →	-1.155	-0.655	.006	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,461 associations by consensus.

Exploration

HOXC6 survival (RNA) · tumor vs normal (RNA) · all HOXC6 data types