HOXC5

Across TCGA patient cohorts, HOXC5 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,823 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HOXC5-associated proteins across cancer lineages are CRYBG3_S931, FBLN2, and HOXC10_S189. Each is linked with HOXC5 in more than 3 cancer types. Because this analysis shows association rather than direction, both HOXC5-to-partner and partner-to-HOXC5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXC5 versus CRYBG3_S931 in BRCA, with a Pearson correlation of -0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXC5→partner) and Y-score (partner→HOXC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CRYBG3_S931 →	-0.511	-0.432	.001	<.001	3	4
CCRCC	FBLN2 →	+0.643	+0.301	.008	.002	3	4
UCEC	HOXC10_S189 →	+1.828	+1.221	<.001	<.001	3	4
LSCC	ESF1 →	+0.428	+0.252	<.001	<.001	3	4
LSCC	TPX2 →	+0.567	+0.309	<.001	.001	3	3
OV	POGZ →	+0.212	+0.224	.006	.009	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,823 associations by consensus.

HOXC5 vs CRYBG3_S931 — BRCA

Explore this scatter interactively →