HOXB7

Across TCGA patient cohorts, HOXB7 protein abundance is significantly associated with the RNA expression of many other genes, with 3,900 significant associations in total. COAD shows the largest number of these associations.

The most reproducible HOXB7-associated genes across cancer lineages are HOXB6, MFSD14B, and HOXB4. Each is linked with HOXB7 in more than 2 cancer types. Because this analysis shows association rather than direction, both HOXB7-to-partner and partner-to-HOXB7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXB7 versus HOXB6 in UCEC, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXB7→partner) and Y-score (partner→HOXB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HOXB6 →	+2.017	+1.193	<.001	.001	3	3
LSCC	MFSD14B →	+0.860	+0.862	.002	.002	3	3
UCEC	HOXB4 →	+2.260	+1.260	<.001	.003	3	3
OV	EPS15L1 →	+0.711	+1.139	.007	.003	3	3
HNSC	TYW5 →	+0.895	+1.879	<.001	<.001	3	3
LSCC	TRA2B →	+1.026	+0.947	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,900 associations by consensus.

HOXB7 vs HOXB6 — UCEC

Explore this scatter interactively →