HOXB6

Across TCGA patient cohorts, HOXB6 protein abundance is significantly associated with the RNA expression of many other genes, with 16,404 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HOXB6-associated genes across cancer lineages are HOXB5, HOXB4, and HOXB-AS3. Each is linked with HOXB6 in more than 3 cancer types. Because this analysis shows association rather than direction, both HOXB6-to-partner and partner-to-HOXB6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXB6 versus HOXB5 in OV, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXB6→partner) and Y-score (partner→HOXB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HOXB5 →	+2.500	+1.338	<.001	<.001	3	4
OV	HOXB4 →	+2.388	+1.178	.004	.006	3	4
LUAD	HOXB-AS3 →	+2.117	+1.026	<.001	.001	3	4
OV	HOXB3 →	+2.445	+1.251	<.001	.001	3	3
OV	STX17 →	+0.716	+0.934	.004	.003	3	3
OV	HOXB-AS2 →	+2.280	+1.291	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,404 associations by consensus.

HOXB6 vs HOXB5 — OV

Explore this scatter interactively →