HOXB6

Across TCGA cell cohorts, HOXB6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,019 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible HOXB6-associated GO terms across cancer lineages are Anterior/posterior pattern specification, Transposition, and Glycosaminoglycan catabolic process. Each is linked with HOXB6 in more than 8 cancer types. Because this analysis shows association rather than direction, both HOXB6-to-partner and partner-to-HOXB6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Anterior/posterior pattern specification grouped by HOXB6-low versus HOXB6-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXB6→partner) and Y-score (partner→HOXB6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Anterior/posterior pattern specification →	+0.050	+1.590	.003	.002	3	9
SOFT_TISSUE	Transposition →	-0.742	-1.385	.003	.006	3	7
SOFT_TISSUE	Glycosaminoglycan catabolic process →	+0.118	+1.292	.002	.009	3	7
KIDNEY	Positive regulation of alpha-beta T cell differentiation →	+0.078	+1.176	<.001	.008	3	6
STOMACH	Regionalization →	+0.043	+2.064	<.001	<.001	3	6
BLOOD_Leukemia	Purine ribonucleotide biosynthetic process →	+0.058	+0.860	<.001	.009	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,019 associations by consensus.

Anterior/posterior pattern specification by HOXB6 expression — KIDNEY

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