HOXB5

Across TCGA patient cohorts, HOXB5 RNA expression is significantly associated with the RNA expression of many other genes, with 17,503 significant associations in total. ACC shows the largest number of these associations.

The most reproducible HOXB5-associated genes across cancer lineages are HOXB6, HOXB-AS3, and HOXB3. Each is linked with HOXB5 in more than 33 cancer types. Because this analysis shows association rather than direction, both HOXB5-to-partner and partner-to-HOXB5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXB5 versus HOXB6 in LAML, with a Pearson correlation of 0.97.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXB5→partner) and Y-score (partner→HOXB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	HOXB6 →	+3.784	+3.829	<.001	<.001	3	34
LAML	HOXB-AS3 →	+3.890	+3.869	<.001	<.001	3	32
LAML	HOXB3 →	+4.153	+3.511	<.001	<.001	3	31
CHOL	HOXB7 →	+2.427	+1.362	<.001	<.001	3	31
UCS	HOXB8 →	+4.206	+3.626	<.001	<.001	3	31
SCLC	HOXB9 →	+3.479	+2.787	<.001	<.001	3	30

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,503 associations by consensus.

HOXB5 vs HOXB6 — LAML

Explore this scatter interactively →