HOXB5

Across TCGA patient cohorts, HOXB5 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,807 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HOXB5-associated proteins across cancer lineages are HOXB6, PALLD, and RAI14. Each is linked with HOXB5 in more than 3 cancer types. Because this analysis shows association rather than direction, both HOXB5-to-partner and partner-to-HOXB5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXB5 versus HOXB6 in OV, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXB5→partner) and Y-score (partner→HOXB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HOXB6 →	+1.338	+2.500	<.001	<.001	3	4
CCRCC	PALLD →	+0.686	+0.434	<.001	<.001	3	4
BRCA	RAI14 →	+0.429	+1.060	<.001	<.001	3	4
BRCA	SEPTIN8 →	+0.288	+1.083	<.001	<.001	3	4
UCEC	HOXB4 →	+1.099	+2.474	.002	<.001	3	4
CCRCC	VCL_S726 →	+0.666	+0.525	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,807 associations by consensus.

HOXB5 vs HOXB6 — OV

Explore this scatter interactively →