HOXB5

Across TCGA patient cohorts, HOXB5 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible HOXB5-associated genes across cancer lineages are Pericytes and Th2 cells. Each is linked with HOXB5 in more than 1 cancer types. Because this analysis shows association rather than direction, both HOXB5-to-partner and partner-to-HOXB5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pericytes grouped by HOXB5-low versus HOXB5-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXB5→partner) and Y-score (partner→HOXB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Pericytes →	+0.090	+3.160	.004	.024	3	1
UCEC	Th2 cells →	+0.329	+3.008	<.001	.019	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Pericytes by HOXB5 expression — SKCM

Explore this box plot interactively →