HOXB1

Across TCGA patient cohorts, HOXB1 RNA expression is significantly associated with the RNA expression of many other genes, with 9,282 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible HOXB1-associated genes across cancer lineages are HOXB3, HOXB2, and HOXB-AS1. Each is linked with HOXB1 in more than 18 cancer types. Because this analysis shows association rather than direction, both HOXB1-to-partner and partner-to-HOXB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXB1 versus HOXB3 in LAML, with a Pearson correlation of 0.49.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXB1→partner) and Y-score (partner→HOXB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	HOXB3 →	+2.633	+0.226	<.001	<.001	3	19
LAML	HOXB2 →	+2.323	+0.251	<.001	<.001	3	16
LAML	HOXB-AS1 →	+1.773	+0.198	<.001	<.001	3	16
UCEC	HOXB8 →	+1.850	+0.159	<.001	<.001	3	16
LAML	HOXB-AS2 →	+2.609	+0.209	<.001	<.001	3	14
LAML	HOXB-AS3 →	+2.387	+0.249	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,282 associations by consensus.

HOXB1 vs HOXB3 — LAML

Explore this scatter interactively →