HOXB1

Across TCGA patient cohorts, HOXB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,959 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HOXB1-associated GO terms across cancer lineages are Embryonic organ morphogenesis, Embryonic skeletal system development, and Morphogenesis of a polarized epithelium. Each is linked with HOXB1 in more than 14 cancer types. Because this analysis shows association rather than direction, both HOXB1-to-partner and partner-to-HOXB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Embryonic organ morphogenesis grouped by HOXB1-low versus HOXB1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXB1→partner) and Y-score (partner→HOXB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Embryonic organ morphogenesis →	+0.038	+0.118	<.001	<.001	3	15
LAML	Embryonic skeletal system development →	+0.053	+0.227	<.001	.002	3	14
STAD	Morphogenesis of a polarized epithelium →	+0.047	+0.142	<.001	<.001	3	14
STAD	Inclusion body assembly →	+0.057	+0.161	<.001	<.001	3	13
STAD	Signal transduction by p53 class mediator →	+0.061	+0.127	<.001	<.001	3	13
STAD	Obsolete histone methylation →	+0.058	+0.112	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,959 associations by consensus.

Embryonic organ morphogenesis by HOXB1 expression — STAD

Explore this box plot interactively →