HOXB1

Across TCGA cell cohorts, HOXB1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,503 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible HOXB1-associated genes across cancer lineages are EIF1B, BIN3, and IRAK1. Each is linked with HOXB1 in more than 4 cancer types. Because this analysis shows association rather than direction, both HOXB1-to-partner and partner-to-HOXB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXB1 versus EIF1B in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.89.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXB1→partner) and Y-score (partner→HOXB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	EIF1B →	+0.959	+1.373	.001	.003	3	5
OESOPHAGUS	BIN3 →	-0.940	-0.943	<.001	.001	3	4
LUNG_NSCLC_LUAD	IRAK1 →	-1.102	-1.068	.001	.003	3	4
LARGE_INTESTINE	GYS1 →	-0.752	-0.889	<.001	.004	3	4
STOMACH	NPHP3 →	-1.041	-1.450	.005	.006	3	3
STOMACH	FLYWCH1 →	-0.890	-1.450	.006	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,503 associations by consensus.

HOXB1 vs EIF1B — UPPER_AERODIGESTIVE_TRACT

Explore this scatter interactively →