HOXA9

Across TCGA patient cohorts, HOXA9 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,125 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HOXA9-associated GO terms across cancer lineages are Embryonic skeletal system morphogenesis, Anterior/posterior pattern specification, and Proximal/distal pattern formation. Each is linked with HOXA9 in more than 19 cancer types. Because this analysis shows association rather than direction, both HOXA9-to-partner and partner-to-HOXA9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Embryonic skeletal system morphogenesis grouped by HOXA9-low versus HOXA9-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXA9→partner) and Y-score (partner→HOXA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Embryonic skeletal system morphogenesis →	+0.042	+1.100	<.001	<.001	3	20
LAML	Anterior/posterior pattern specification →	+0.043	+2.507	<.001	<.001	3	19
GBM	Proximal/distal pattern formation →	+0.058	+1.297	<.001	<.001	3	19
TGCT	Urogenital system development →	+0.050	+1.391	<.001	<.001	3	19
TGCT	Appendage morphogenesis →	+0.049	+1.341	<.001	<.001	3	19
TGCT	Male sex differentiation →	+0.034	+1.700	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,125 associations by consensus.

Embryonic skeletal system morphogenesis by HOXA9 expression — STAD

Explore this box plot interactively →