HOXA5

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, HOXA5 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,902 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HOXA5-associated GO terms across cancer lineages are Embryonic neurocranium morphogenesis, mRNA transport, and Anterior/posterior pattern specification. Each is linked with HOXA5 in more than 7 cancer types. Because this analysis shows association rather than direction, both HOXA5-to-partner and partner-to-HOXA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Embryonic neurocranium morphogenesis grouped by HOXA5-low versus HOXA5-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXA5→partner) and Y-score (partner→HOXA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CNSEmbryonic neurocranium morphogenesis →-0.250-1.558<.001<.00138
BREASTmRNA transport →+0.091+1.198<.001<.00137
KIDNEYAnterior/posterior pattern specification →+0.049+1.489<.001<.00128
CNSProtein localization to microtubule →+0.083+1.052.001.00337
LARGE_INTESTINEPre-mRNA catabolic process →+0.118+1.729.006.00237
LUNG_NSCLC_LUADRegionalization →+0.024+0.750.003.00928
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,902 associations by consensus.

Embryonic neurocranium morphogenesis by HOXA5 expression — CNS

Box plot of Embryonic neurocranium morphogenesis in HOXA5-low vs HOXA5-high samples in CNS.

Explore this box plot interactively →

Exploration