HOXA13

Across TCGA patient cohorts, HOXA13 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,286 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HOXA13-associated proteins across cancer lineages are IGF2BP3, PLCG2, and SUSD2. Each is linked with HOXA13 in more than 4 cancer types. Because this analysis shows association rather than direction, both HOXA13-to-partner and partner-to-HOXA13 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXA13 versus IGF2BP3 in CCRCC, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXA13→partner) and Y-score (partner→HOXA13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	IGF2BP3 →	+1.487	+0.785	<.001	<.001	3	5
LSCC	PLCG2 →	-0.399	-0.865	.004	<.001	3	3
GBM	SUSD2 →	-0.581	-0.671	.002	.002	3	3
HNSC	TOP2A →	+0.640	+0.631	<.001	.002	3	3
HNSC	IRS2_S608 →	+0.851	+0.698	.001	.003	3	3
CCRCC	AP3B2_S272 →	+0.955	+0.555	.003	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,286 associations by consensus.

HOXA13 vs IGF2BP3 — CCRCC

Explore this scatter interactively →