HOXA11

Across TCGA cell cohorts, HOXA11 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HOXA11-associated genes across cancer lineages are LCE2A. Each is linked with HOXA11 in more than 1 cancer types. Because this analysis shows association rather than direction, both HOXA11-to-partner and partner-to-HOXA11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LCE2A grouped by HOXA11-low versus HOXA11-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXA11→partner) and Y-score (partner→HOXA11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	LCE2A →	+0.053	+4.969	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

LCE2A by HOXA11 expression — BLOOD_Leukemia

Explore this box plot interactively →