HOXA10

Across TCGA patient cohorts, HOXA10 protein abundance is significantly associated with the RNA expression of many other genes, with 1,613 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HOXA10-associated genes across cancer lineages are SNORD113-1, MTND4LP9, and CRTAM. Each is linked with HOXA10 in more than 1 cancer types. Because this analysis shows association rather than direction, both HOXA10-to-partner and partner-to-HOXA10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXA10 versus SNORD113-1 in UCEC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXA10→partner) and Y-score (partner→HOXA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNORD113-1 →	+1.630	+0.578	<.001	<.001	3	2
UCEC	MTND4LP9 →	+1.180	+0.563	<.001	<.001	3	2
CCRCC	CRTAM →	-0.870	-0.535	.003	.005	3	1
CCRCC	PUS3 →	+0.267	+0.417	.005	.004	3	1
CCRCC	CDX1 →	-0.154	-0.317	<.001	.003	3	1
CCRCC	SET →	+0.251	+0.373	.004	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,613 associations by consensus.

HOXA10 vs SNORD113-1 — UCEC

Explore this scatter interactively →