HOXA10

Across TCGA cell cohorts, HOXA10 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,269 significant associations in total. BONE shows the largest number of these associations.

The most reproducible HOXA10-associated GO terms across cancer lineages are Embryonic skeletal joint morphogenesis, Cellular response to forskolin, and Embryonic skeletal joint development. Each is linked with HOXA10 in more than 8 cancer types. Because this analysis shows association rather than direction, both HOXA10-to-partner and partner-to-HOXA10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Embryonic skeletal joint morphogenesis grouped by HOXA10-low versus HOXA10-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXA10→partner) and Y-score (partner→HOXA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Embryonic skeletal joint morphogenesis →	-0.275	-2.037	<.001	<.001	3	9
KIDNEY	Cellular response to forskolin →	+0.167	+2.154	<.001	<.001	3	8
BLOOD_Lymphoma	Embryonic skeletal joint development →	-0.269	-2.211	<.001	<.001	3	7
BONE	Positive regulation of matrix metallopeptidase secretion →	-0.282	-2.507	<.001	<.001	3	7
SOFT_TISSUE	Regulation of smooth muscle cell migration →	+0.120	+1.527	<.001	<.001	3	7
BREAST	Negative regulation of defense response →	+0.079	+2.147	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,269 associations by consensus.

Embryonic skeletal joint morphogenesis by HOXA10 expression — BLOOD_Lymphoma

Explore this box plot interactively →