HOXA1

Across TCGA patient cohorts, HOXA1 RNA expression is significantly associated with the RNA expression of many other genes, with 17,913 significant associations in total. ACC shows the largest number of these associations.

The most reproducible HOXA1-associated genes across cancer lineages are HOTAIRM1, SKAP2, and HOXA3. Each is linked with HOXA1 in more than 31 cancer types. Because this analysis shows association rather than direction, both HOXA1-to-partner and partner-to-HOXA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXA1 versus HOTAIRM1 in UCEC, with a Pearson correlation of 0.73.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXA1→partner) and Y-score (partner→HOXA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HOTAIRM1 →	+2.402	+1.066	<.001	<.001	3	32
LAML	SKAP2 →	+1.972	+1.067	<.001	<.001	3	32
LAML	HOXA3 →	+2.904	+1.274	<.001	<.001	3	31
LAML	HOXA2 →	+1.773	+1.312	<.001	<.001	3	30
LAML	HOXA4 →	+2.312	+1.227	<.001	<.001	3	30
LAML	HOXA-AS2 →	+2.383	+1.144	<.001	<.001	3	30

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,913 associations by consensus.

HOXA1 vs HOTAIRM1 — UCEC

Explore this scatter interactively →