HOXA1

Across TCGA patient cohorts, HOXA1 protein abundance is significantly associated with the RNA expression of many other genes, with 395 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HOXA1-associated genes across cancer lineages are C22orf31, OGDH, and CCNJ. Each is linked with HOXA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HOXA1-to-partner and partner-to-HOXA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOXA1 versus C22orf31 in PDAC, with a Pearson correlation of -0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOXA1→partner) and Y-score (partner→HOXA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	C22orf31 →	-0.189	-1.424	<.001	<.001	3	1
PDAC	OGDH →	+0.566	+1.606	.002	.002	3	1
PDAC	CCNJ →	-0.376	-1.579	<.001	.002	3	1
PDAC	PITX3 →	-0.091	-1.155	.007	.003	3	1
PDAC	LRP2BP →	-0.534	-2.004	.001	<.001	3	1
PDAC	FBXO3 →	-0.414	-1.348	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 395 associations by consensus.

HOXA1 vs C22orf31 — PDAC

Explore this scatter interactively →