HORMAD1

Across TCGA cell cohorts, HORMAD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,081 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible HORMAD1-associated GO terms across cancer lineages are Regulation of homologous chromosome segregation, Meiotic recombination checkpoint signaling, and Response to L-phenylalanine derivative. Each is linked with HORMAD1 in more than 12 cancer types. Because this analysis shows association rather than direction, both HORMAD1-to-partner and partner-to-HORMAD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of homologous chromosome segregation grouped by HORMAD1-low versus HORMAD1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HORMAD1→partner) and Y-score (partner→HORMAD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of homologous chromosome segregation →	-0.345	-2.136	<.001	<.001	3	13
URINARY_TRACT	Meiotic recombination checkpoint signaling →	-0.245	-1.778	<.001	.001	3	7
BREAST	Response to L-phenylalanine derivative →	+0.108	+1.260	<.001	.007	3	6
LUNG_NSCLC_LUAD	Negative regulation of meiotic nuclear division →	-0.160	-1.253	<.001	<.001	3	4
LUNG_NSCLC_LUSC	tRNA methylation →	+0.044	+2.518	.009	.006	2	4
BLOOD_Lymphoma	Regulation of intracellular steroid hormone receptor signaling pathway →	+0.053	+0.140	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,081 associations by consensus.

Regulation of homologous chromosome segregation by HORMAD1 expression — OESOPHAGUS

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