Across TCGA cell cohorts, HOMEZ RNA expression is significantly associated with the go_rna of many other GO terms, with 3,013 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible HOMEZ-associated GO terms across cancer lineages are Protein linear polyubiquitination, Response to starvation, and Positive regulation of autophagy. Each is linked with HOMEZ in more than 12 cancer types. Because this analysis shows association rather than direction, both HOMEZ-to-partner and partner-to-HOMEZ results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HOMEZ→partner) and Y-score (partner→HOMEZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Protein linear polyubiquitination →	+0.167	+0.761	<.001	<.001	3	13
KIDNEY	Response to starvation →	+0.042	+0.701	<.001	<.001	3	9
PANCREAS	Positive regulation of autophagy →	+0.044	+0.720	.005	.005	3	8
OESOPHAGUS	Negative regulation of DNA-templated transcription, elongation →	+0.104	+1.213	.006	<.001	3	8
OVARY	Branched-chain amino acid metabolic process →	+0.076	+0.487	<.001	<.001	3	8
BLOOD_Myeloma	Endothelial to hematopoietic transition →	+0.147	+0.952	.004	.002	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,013 associations by consensus.

Exploration

HOMEZ survival (RNA) · tumor vs normal (RNA) · all HOMEZ data types