HOMER3

Across TCGA patient cohorts, HOMER3 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,728 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HOMER3-associated proteins across cancer lineages are HOMER3_S256, MMP14, and FSCN1. Each is linked with HOMER3 in more than 8 cancer types. Because this analysis shows association rather than direction, both HOMER3-to-partner and partner-to-HOMER3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOMER3 versus HOMER3_S256 in HNSC, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HOMER3→partner) and Y-score (partner→HOMER3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HOMER3_S256 →	+0.720	+0.693	<.001	<.001	3	9
HNSC	MMP14 →	+0.484	+0.854	<.001	<.001	3	7
HNSC	FSCN1 →	+0.557	+0.734	<.001	<.001	3	6
PDAC	PLOD1 →	+0.586	+0.494	<.001	<.001	3	6
BRCA	PTK7 →	+0.484	+0.712	.001	.003	3	6
BRCA	COLGALT1 →	+0.465	+0.783	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,728 associations by consensus.

HOMER3 vs HOMER3_S256 — HNSC

Explore this scatter interactively →