HOMER3

Across TCGA patient cohorts, HOMER3 protein abundance is significantly associated with the RNA expression of many other genes, with 14,776 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible HOMER3-associated genes across cancer lineages are COL5A2, COL5A1, and ITGB1. Each is linked with HOMER3 in more than 7 cancer types. Because this analysis shows association rather than direction, both HOMER3-to-partner and partner-to-HOMER3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HOMER3 versus COL5A2 in COAD, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOMER3→partner) and Y-score (partner→HOMER3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	COL5A2 →	+1.085	+0.574	<.001	.001	3	8
LSCC	COL5A1 →	+1.067	+0.300	.001	<.001	3	7
LSCC	ITGB1 →	+0.720	+0.318	<.001	<.001	3	7
COAD	ITGA5 →	+1.171	+0.638	<.001	.001	2	8
HNSC	HTRA1 →	+0.992	+0.477	<.001	<.001	3	7
LUAD	TPM4 →	+0.588	+0.230	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,776 associations by consensus.

HOMER3 vs COL5A2 — COAD

Explore this scatter interactively →