Across TCGA patient cohorts, HOATZ RNA expression is significantly associated with the protein abundance of many other proteins, with 9,669 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HOATZ-associated proteins across cancer lineages are SPATA18_S276, C7orf57_S209, and CAPS. Each is linked with HOATZ in more than 5 cancer types. Because this analysis shows association rather than direction, both HOATZ-to-partner and partner-to-HOATZ results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HOATZ→partner) and Y-score (partner→HOATZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SPATA18_S276 →	+1.248	+0.343	<.001	<.001	3	6
LSCC	C7orf57_S209 →	+1.529	+0.463	<.001	<.001	3	5
UCEC	CAPS →	+0.944	+1.500	.001	<.001	3	5
UCEC	DNALI1 →	+0.909	+1.684	<.001	<.001	3	5
LSCC	TTC25_S616 →	+1.201	+0.710	<.001	<.001	3	5
UCEC	TPPP3 →	+1.452	+1.526	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,669 associations by consensus.

Exploration

HOATZ survival (RNA) · tumor vs normal (RNA) · all HOATZ data types