Across TCGA patient cohorts, HOATZ mutation is significantly associated with the RNA expression of many other genes, with 1,956 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HOATZ-associated genes across cancer lineages are RN7SL650P, FOXC2-AS1, and RNA5SP420. Each is linked with HOATZ in more than 1 cancer types. Because this analysis shows association rather than direction, both HOATZ-to-partner and partner-to-HOATZ results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HOATZ→partner) and Y-score (partner→HOATZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL650P →	+0.386	+2.442	<.001	<.001	3	2
SKCM	FOXC2-AS1 →	+0.454	+4.386	<.001	<.001	3	2
UCEC	RNA5SP420 →	+0.630	+2.436	<.001	<.001	3	2
UCEC	CCL5 →	+0.952	+2.716	.005	.003	3	1
UCEC	LINC01607 →	-0.714	-3.885	<.001	<.001	3	1
UCEC	POM121C →	+0.453	+3.724	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,956 associations by consensus.

Exploration

HOATZ survival (RNA) · tumor vs normal (RNA) · all HOATZ data types