Across TCGA cell cohorts, HOATZ RNA expression is significantly associated with the go_rna of many other GO terms, with 602 significant associations in total. BONE shows the largest number of these associations.

The most reproducible HOATZ-associated GO terms across cancer lineages are Positive regulation of nucleotide biosynthetic process, Regulation of amyloid fibril formation, and Positive regulation of purine nucleotide biosynthetic process. Each is linked with HOATZ in more than 5 cancer types. Because this analysis shows association rather than direction, both HOATZ-to-partner and partner-to-HOATZ results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HOATZ→partner) and Y-score (partner→HOATZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Positive regulation of nucleotide biosynthetic process →	+0.087	+0.273	<.001	.007	2	6
LARGE_INTESTINE	Regulation of amyloid fibril formation →	+0.109	+0.163	<.001	.002	3	5
CNS	Positive regulation of purine nucleotide biosynthetic process →	+0.087	+0.273	<.001	.007	2	6
CNS	Positive regulation of ATP biosynthetic process →	+0.086	+0.273	<.001	.007	2	6
BONE	Negative regulation of chemotaxis →	+0.115	+0.234	.003	.006	3	5
STOMACH	CD8-positive, alpha-beta T cell activation →	+0.101	+0.049	.001	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 602 associations by consensus.

Exploration

HOATZ survival (RNA) · tumor vs normal (RNA) · all HOATZ data types