HNRNPLL

Across TCGA patient cohorts, HNRNPLL mutation is significantly associated with the RNA expression of many other genes, with 2,455 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HNRNPLL-associated genes across cancer lineages are GAGE2E, PINCR, and RNA5SP410. Each is linked with HNRNPLL in more than 1 cancer types. Because this analysis shows association rather than direction, both HNRNPLL-to-partner and partner-to-HNRNPLL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAGE2E grouped by HNRNPLL-low versus HNRNPLL-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPLL→partner) and Y-score (partner→HNRNPLL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	GAGE2E →	+0.105	+5.197	.005	.003	3	2
UCEC	PINCR →	+0.318	+2.159	<.001	.001	3	2
UCEC	RNA5SP410 →	+0.493	+2.011	.002	.005	3	2
UCEC	RNA5SP417 →	+0.438	+2.574	<.001	<.001	3	2
UCEC	RNU6-1213P →	+0.155	+3.462	<.001	.002	3	2
UCEC	YTHDF3-AS1 →	+0.679	+2.468	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,455 associations by consensus.

GAGE2E by HNRNPLL expression — LUAD

Explore this box plot interactively →